Good news for Wolftard and T1B's other old farts

It's the 17th Anniversary for T1B - Fuckin' A

Moderator: Jesus H Christ

Post Reply
User avatar
Screw_Michigan
Angry Snowflake
Posts: 20362
Joined: Wed Feb 17, 2010 2:37 am
Location: 20011

Good news for Wolftard and T1B's other old farts

Post by Screw_Michigan »

Takes the phrase "eat shit" to a whole new level

Fecal Transplants Reverse Hallmarks of Aging

https://neurosciencenews.com/fecal-tran ... ing-20522/
Summary: Transplanting fecal microbiota from young mice to older mice reversed hallmark signs of aging in the gut, brains, and eyes. Transplanting the fecal microbiota from old to young mice had the reverse effect, inducing inflammation in the brain and depleting a key protein associated with healthy vision.

Source: University of East Anglia

In the search for eternal youth, poo transplants may seem like an unlikely way to reverse the aging process.

However, scientists at the Quadram Institute and the University of East Anglia have provided evidence, from research in mice, that transplanting fecal microbiota from young into old mice can reverse hallmarks of aging in the gut, eyes, and brain.

In the reverse experiment, microbes from aged mice induced inflammation in the brain of young recipients and depleted a key protein required for normal vision.

These findings show that gut microbes play a role in the regulating some of the detrimental effects of aging and open up the possibility of gut microbe-based therapies to combat decline in later life.

Prof Simon Carding, from UEA’s Norwich Medical School and head of the Gut Microbes and Health Research Program at the Quadram Institute, said: “This ground-breaking study provides tantalizing evidence for the direct involvement of gut microbes in aging and the functional decline of brain function and vision and offers a potential solution in the form of gut microbe replacement therapy.”

It has been known for some time that the population of microbes that we carry around in our gut, collectively called the gut microbiota, is linked to health. Most diseases are associated with changes in the types and behavior of bacteria, viruses, fungi and other microbes in an individual’s gut.

Some of these changes in microbiota composition happen as we age, adversely affecting metabolism and immunity, and this has been associated with age-related disorders including inflammatory bowel diseases, along with cardiovascular, autoimmune, metabolic and neurodegenerative disorders.

To better understand the effects of these changes in the microbiota in old age, scientists from the Quadram Institute transferred the gut microbes from aged mice into healthy young mice, and vice versa. They then looked at how this affected inflammatory hallmarks of aging in the gut, brain and eye, which suffer from declining function in later life.

The study, published in the journal Microbiome, found that the microbiota from old donors led to loss of integrity of the lining of the gut, allowing bacterial products to cross into the circulation, which results in triggering the immune system and inflammation in the brain and eyes.

Age-related chronic inflammation, known as inflammaging, has been associated with the activation of specific immune cells found in brain. These cells were also over-activated in the young mice who received aged microbiome transplants.

In the eye, the team also found specific proteins associated with retinal degeneration were elevated in the young mice receiving microbiota from old donors.

In old mice, these detrimental changes in the gut, eye and brain could be reversed by transplanting the gut microbiota from young mice.

In ongoing studies, the team are now working to understand how long these positive effects can last, and to identify the beneficial components of the young donor microbiota and how they impact on organs distant from the gut.

The microbiota of young mice, and the old mice who received young microbiota transplants were enriched in beneficial bacteria that have previously been associated with good health in both mice and humans.
kcdave wrote: Sat Sep 09, 2023 8:05 am
I was actually going to to join in the best bets activity here at good ole T1B...The guy that runs that contest is a fucking prick
Derron wrote: Sat Oct 03, 2020 3:07 pm
You are truly one of the worst pieces of shit to ever post on this board. Start giving up your paycheck for reparations now and then you can shut the fuck up about your racist blasts.
Post Reply